How often does fibrosarcoma occur in the US?
Only approximately 5% of all primary bone sarcomas are fibrosarcoma. 2 According to data compiled by the NCI in the SEER database between the years 2000 – 2004, the age-adjusted incidence of all bone and joint sarcoma was 0.9 per 100,000 men and women per year.
How is fibrosarcoma a spindle cell cancer?
Fibrosarcoma is part of a larger collection of cancers known as sarcomas. Sarcomas are spindle cell malignancies of mesenchymal cell origin and are named and classified after the predominant cell line that is present.
Is there such a thing as fibrosarcoma of bone?
Fibrosarcoma of bone is a rare primary malignancy. It shares imaging and clinical features with several other bone pathologies. Fibrosarcoma shares histological features with other bone tumors and often cannot be distinguished from such lesions other than by an experienced musculoskeletal pathologist.
What’s the difference between MFH and fibrosarcoma?
Malignant fibrous histiocytoma (MFH) of bone is a distinct entity from fibrosarcoma and was first described in the 1970’s. 5 Like fibrosarcoma, MFH more commonly arises in soft tissue (soft tissue sarcoma). Histologically, these lesions are composed of a heterogeneous population of cells.
Malignant fibrous histiocytoma (MFH) of bone is a distinct entity from fibrosarcoma and was first described in the 1970’s. 5 Like fibrosarcoma, MFH more commonly arises in soft tissue (soft tissue sarcoma). Histologically, these lesions are composed of a heterogeneous population of cells.
Is it possible to confuse osteosarcoma with fibrosarcoma?
Fibrosarcoma can be confused with osteosarcoma because both can affect young patients, including patients in the second decade of life (ages 10 – 19). Both have a predilection for the distal femur and radiographically can appear as aggressive lesions.
What is the age distribution of soft tissue sarcomas?
Age Distribution of Soft Tissue Sarcomas in Children Aged 0 to 19 Years (SEER 2000–2015) a pPNET = peripheral primitive neuroectodermal tumors; SEER = Surveillance, Epidemiology, and End Results. a Source: SEER database.
What are the treatment options for infantile fibrosarcoma?
Treatment options for infantile fibrosarcoma include the following: 1 Surgery followed by observation. 2 Surgery followed by chemotherapy. 3 Chemotherapy followed by surgery. 4 Targeted therapy.